Glutathione: The Essential Antioxidant for Health and Anti-Ageing

OT&P's Longevity Medical Examination, conducts several unique tests are included that are often absent from standard medical evaluations. These tests encompass Lipoprotein (a), Apolipoprotein B, VO2 Max, Glutathione, Reduced Glutathione, and DEXA body composition. Notably, glutathione serves as the body’s master antioxidant, and oxidation is a primary factor in the ageing process.

What Is Glutathione?

Glutathione is a small molecule composed of three amino acids: glutamic acid, cysteine, and glycine. It is naturally produced by the body and is found in nearly every cell, making it one of the most vital and abundant antioxidants in living organisms. Glutathione exists in two primary forms: Reduced Glutathione (GSH), the active antioxidant form, and Oxidised Glutathione (GSSG), which occurs after it has neutralised free radicals.

Understanding Reduced Glutathione

Reduced Glutathione is the biologically active form of glutathione. It features a free thiol group (-SH) that enables it to act as a potent antioxidant, neutralising harmful free radicals and reactive oxygen species in the body. The body continuously recycles oxidised glutathione (GSSG) back into its reduced form (GSH) to sustain cellular health.

Why Reduced Glutathione Matters

Reduced Glutathione is essential for several reasons:

Master Antioxidant: It protects cells from oxidative stress and damage caused by free radicals, which are associated with ageing, inflammation, and various chronic diseases.

Detoxification: Glutathione binds to toxins, heavy metals, and waste products, facilitating their elimination from the body, particularly through the liver.

Immune System Support: It plays a crucial role in enhancing immune cell function and defending the body against infections.

Regeneration of Other Antioxidants: Glutathione aids in regenerating vitamins C and E, boosting the body’s overall antioxidant capacity.

Cellular Health and Repair: It supports DNA synthesis and repair, protein synthesis, and cell division.

Anti-Ageing Effects: By reducing oxidative stress, glutathione may slow cellular ageing and improve skin health and appearance.
Energy Production: It supports mitochondrial function, which is vital for energy production in cells.

Maintaining adequate levels of glutathione—especially in its reduced form—is crucial for detoxification, immune function, and combating oxidative stress, one of the key drivers of ageing. By understanding the importance of glutathione, individuals can take proactive steps to support their health and longevity. It's worth meeting with a doctor to learn more about your glutathione levels and overall health for a longer, healthier life.