Contrast agents are commonly used during medical imaging procedures such as X-rays, CT (Computed Tomography) or MRI (Magnetic Resonance Imaging) scans to enhance image clarity and diagnostic accuracy. Many people have concerns about the use of contrast agents, particularly whether they might cause harm if not properly eliminated from the body. This article explains how contrast agents are excreted and offers practical dietary advice to help you prepare your body before and after a CT or MRI scan, aiding quicker recovery.
How Are Contrast Agents Excreted from the Body?
Commonly used contrast agents can be broadly categorised into barium sulphate-based, iodine-based, and gadolinium-based agents. These are typically expelled from the body via the digestive system or kidneys:
- Barium sulphate-based contrast agents have low water solubility and are not absorbed by the gastrointestinal tract. They are excreted via the digestive system, usually within 24 hours, and may cause stools to appear grey or white for several days.
- Iodine-based contrast agents are distributed in the extracellular fluid in the body and eliminated through the kidneys. In individuals with normal kidney function, approximately 50% is excreted within two hours, with complete elimination typically occurring within 24 hours.
- Gadolinium-based contrast agents are primarily expelled via the kidneys, with over 95% eliminated in urine within 24 hours. A small proportion (less than 4%) may be excreted in the stool.
Why Is Dietary Management Important After an Imaging Scan with Contrast?
Proper dietary management can help accelerate the elimination of contrast agents and reduce the risk of adverse interactions between certain foods or supplements and the contrast agent. Additionally, replenishing essential vitamins and minerals supports cellular repair and overall recovery.
Three Key Dietary Tips for Recovery
1. Stay Hydrated
Drinking plenty of water after your scan helps the kidneys flush out contrast agents more efficiently. This also aids to prevent “caking” or thickening and solidifying of barium sulphate in the gastrointestinal tract.
2. Maintain a Balanced Diet
There is no specific diet restrictions so you can eat as usual. If you received a barium sulphate-based agent, increasing your intake of fruits and vegetables may help promote bowel movements.
3. Supplement vitamins and minerals
Contrast agents can cause minor cellular damage to endothelial cells, and laboratory studies have shown that all contrast agents can cause reduced cell viability. Nutrients such as vitamin C, vitamin E, and zinc are beneficial for cellular repair.
Consider incorporating natural foods rich in these nutrients, such as:
- Vitamin C: Citrus fruits, strawberries, broccoli, bell peppers
- Vitamin E: Nuts, vegetable oils, wheat germ
- Zinc: Shellfish, pumpkin seeds, whole grains
Dietary Restrictions for Gadolinium-Based MRI Scans
Research published in Magnetic Resonance Imaging revealed that oxalates may bind with gadolinium ions in contrast agents to form nanoparticles, which can deposit in the skin, kidneys, and brain. While current evidence does not indicate that these nanoparticles cause direct tissue damage, caution is advised.
Oxalate-rich foods include spinach, nuts, chocolate, and certain berries. Additionally, vitamin C can be metabolised into oxalate, which may contribute to increased risk of kidney stone formation when combined with calcium ion. To minimise potential interactions and support complete elimination of contrast agents, it is advisable to avoid excessive intake of vitamin C supplements and oxalate-rich foods within 24 hours prior to an MRI scan.
Conclusion
In most cases, contrast agents are safely eliminated from the body within 24 hours. For individuals in good health with normal kidney function, this is a natural and harmless process. To facilitate efficient and timely clearance, ensure adequate hydration and maintain a nutrient-rich diet. If you have any concerns or specific health conditions, consult your healthcare provider for personalised and best practice advice.
References
- Drugbank, (2021) Barium sulfate. Retrieved 18 June 2025 from https://go.drugbank.com/drugs/DB11150
- St. Paul’s Hospital, (n.d.) 醫療程序須知 – 吞鋇 X 光造影檢查. Retrieved 18 June 2025 from https://www.stpaul.org.hk/storage/media/Forms/Radiology/ZDIC_PIS50_P%20%E9%86%AB%E7%99%82%E7%A8%8B%E5%BA%8F%E9%A0%88%E7%9F%A5%20-%20%E5%90%9E%E9%8B%87X%E5%85%89%E9%80%A0%E5%BD%B1%E6%AA%A2%E6%9F%A5.pdf
- University of Wisconsin-Madison. (2025) Department of Radiology – CT contrast and breastfeeding. Retrieved 18 June 2025 from https://radiology.wisc.edu/ct-contrast-and-breastfeeding/#:~:text=Iodinated%20X%2Dray%20Contrast%20Media,the%20bloodstream%20within%2024%20hours
- Deray, G. (2006). Dialysis and iodinated contrast media. Kidney International, 69, pp.S25–S29.
- Van der Molen AJ, et al., (2023). Waiting times between examinations with intravascularly administered contrast media: a review of contrast media pharmacokinetics and updated ESUR Contrast Media Safety Committee guidelines. European Radiology, 34(4):2512-2523.
- RadiologyInfo.org, (2024) Contrast Materials. Retrieved 18 June 2025 from https://www.radiologyinfo.org/en/info/safety-contrast
- St. Paul’s Hospital, (n.d.) 醫療程序須知 –食道、胃與小腸顯影劑造影. Retrieved 18 June 2025 from https://www.stpaul.org.hk/storage/media/Forms/Radiology/ZDIX_PIS05_P%20%E9%86%AB%E7%99%82%E7%A8%8B%E5%BA%8F%E9%A0%88%E7%9F%A5%20-%20%E9%A3%9F%E9%81%93%E3%80%81%E8%83%83%E8%88%87%E5%B0%8F%E8%85%B8%E9%A1%AF%E5%BD%B1%E5%8A%91%E9%80%A0%E5%BD%B1%20(20220223).pdf
- Andreucci, M., Solomon, R. and Tasanarong, A. (2014). Side Effects of Radiographic Contrast Media: Pathogenesis, Risk Factors, and Prevention. BioMed Research International, 2014(1), pp.1–20.
- AQ Modern Diagnostic Imaging, (2025) What Vitamins to Take after CT scan. Retrieved 18 June 2025 from https://aqmdi.com/what-vitamins-to-take-after-ct-scan/
- NHS, (2020) Vitamins and minerals. Retrieved 18 June 2025 from https://www.nhs.uk/conditions/vitamins-and-minerals/others/
- Islam, M.T. and Tsnobiladze, V, (2024). The Application, Safety, and Recent Developments of Commonly Used Gadolinium-Based Contrast Agents in MRI: A Scoping Review. European Medical Journal, pp.63–73.
- Henderson, I.M., et al., (2025). Precipitation of gadolinium from magnetic resonance imaging contrast agents may be the Brass tacks of toxicity. Magnetic Resonance Imaging, 119(6):110383. http://dx.doi.org/10.1016/j.mri.2025.110383
- Axis Imaging News, (2025). Why Some People Get Sick After an MRI With Contrast May Come Down to Diet. Retrieved 18 June 2025 from https://axisimagingnews.com/radiology-products/imaging-equipment/mri/why-some-people-get-sick-mri-may-come-down-diet-study-finds
Central General Practice
Repulse Bay
Clearwater Bay
BodyWorX Clinic
Central Specialist Clinic
MindWorX Clinic
Partner Clinics
Family Clinic
OT&P Annerley Midwives Clinic
