Skip to content
Ophthalmology at OT&P
Perfecting sight, enhancing vision.
Urology at OT&P
Leading the way in urological health.
Cardiology at OT&P
Guarding hearts, enhancing lives.


Celecoxib is a nonsteroidal anti-inflammatory drug (NSAID).

Last Modified: 21 May 2024

Jump to section:


What is Celecoxib?

Celecoxib is a nonsteroidal anti-inflammatory drug (NSAID) that specifically targets cyclooxygenase- 2 (COX-2) enzymes (a COX-2 inhibitor), reducing inflammation and pain. 

Active ingredient: Celecoxib 

Global Name

Generic name: Celecoxib 
Brand names: Celebrex, Onsenal 


What is Celecoxib used for?

Celecoxib is used for: 

  • Relieving pain and inflammation associated with arthritis 
  • Managing acute pain and menstrual cramps 
  • Reducing the number of colon and rectal polyps in patients with familial adenomatous polyposis, when used as directed by a doctor. 

How do you use Celecoxib?


Celecoxib is available in capsule form. 

Dosage Information:

  • Adults: Dosage varies by condition, typically ranging from 100 mg twice to 200 mg once daily. 
  • Children: Use and dose must be determined by a healthcare provider. 

Suitable for:

  • Children: Safety and effectiveness in pediatric patients have not been established for most conditions. 
  • Adults: Broadly used across adult age groups. 
  • Elderlies: May require lower doses due to increased risk of adverse effects or drug accumulation. 

Not Suitable for:

    • Children: without specific medical advice 
    • Patients with known hypersensitivity to celecoxib, sulfonamides, or other NSAIDs 
    • Individuals with a history of asthma, urticaria, or allergic-type reactions after taking aspirin or other NSAIDs 
    • In the setting of coronary artery bypass graft (CABG) surgery 
    • Individuals with active gastritis, duodenitis or peptic-ulcer disease 
    • Pregnancy: Celecoxib may cause harm to the fetus, particularly in the third trimester, and should not be used by pregnant women unless advised by healthcare professionals in special circumstances  
    • Lactation: It is not known if celecoxib is excreted in human milk. Due to the potential for serious adverse reactions in nursing infants from celecoxib, a decision should be made whether to discontinue nursing or to discontinue the drug, taking into account the importance of the drug to the mother. 

Allergies and Warnings:

Celecoxib should be avoided by those with known hypersensitivity to celecoxib, sulfonamides, or other NSAIDs, and individuals with a history of asthma, urticaria, or allergic-type reactions after taking aspirin or other NSAIDs. It is contraindicated in the setting of coronary artery bypass graft (CABG) surgery. 

Precautions and Interactions:

  • Celecoxib can be taken with or without food. However, taking it with food may help to minimise gastrointestinal discomfort.
  • Celecoxib may interact with other medications such as warfarin, ACE inhibitors, and furosemide. It is contraindicated in patients with active gastrointestinal bleeding. 

Side Effects

Common side effects may include stomach pain, diarrhoea, and indigestion. Serious side effects like heart attack, stroke, and gastrointestinal bleeding can occur. 

Pharmacist Tips

  • Dosage Adherence: Stick to the prescribed dosage and schedule to manage your condition effectively and minimise the risk of side effects. 
  • Awareness of Side Effects: Monitor for signs of stomach ulcers or bleeding, such as bloody stools or coughing up blood, and seek immediate medical attention if they occur. 
  • Drug Interactions: List all your medications and share them with your healthcare provider to avoid potential interactions. 
  • Preventive Measures: Take celecoxib with food or milk to reduce the risk of stomach upset or ulcers. An antacid (e.g. Gaviscon, Maalox), H2-antagonist (e.g. famotidine, ranitidine) or proton pump inhibitor (PPI) (e.g. omeprazole, pantoprazole) may be paired. 
  • Regular Monitoring: Regularly review your treatment with your healthcare provider, especially if you have a history of heart disease or stroke. 
  • Safe Storage: Store celecoxib at room temperature, away from moisture and heat. Keep the medication out of reach of children and pets. 
  • Proper Disposal: Do not keep leftover or expired medication. Find out about take-back programs or consult your pharmacist for disposal instructions.


Where is Celecoxib available in Hong Kong?

Celecoxib is a prescription medication that can be prescribed by healthcare providers.


Is Celecoxib available over the counter? 

No, Celecoxib is a prescription medication unavailable over the counter. 

How long does it take for Celecoxib to work?

Celecoxib typically relieves pain within a few hours, but it may take longer for some conditions to see the full benefits.

Can I drink alcohol while taking Celecoxib?

It's best to avoid alcohol, as it can increase the risk of stomach bleeding when taking NSAIDs like Celecoxib. Discuss any alcohol consumption with your doctor.

Is Celecoxib an opioid medication?

No, Celecoxib is an NSAID, not an opioid medication. It is a non-steroidal anti-inflammatory drug (NSAID). 

This website provides content related to drug use and medicine for informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Do not use the information on this website to diagnose or treat a health problem or disease without consulting a qualified healthcare provider. The website's owners and contributors are not liable for any repercussions, adverse effects, or consequences resulting from the use of any medication or information provided herein.

Back to all drugs

Download the OT&P Digital App

Subscribe to our Newsletter

Our Awards & Accreditations

Happy Company 2024
Caring company logo
Mental Health Logo 1
Good MPF Employer 2022-23_Single Colour