Elantan

Overview

What is Elantan?   

Elantan is a medication primarily used for the treatment of angina pectoris, a condition characterised by chest pain caused by reduced blood flow to the heart. The active ingredient in Elantan is isosorbide mononitrate, which belongs to a class of drugs known as nitrates. Isosorbide mononitrate works by relaxing and widening blood vessels (vasodilator), making it easier for blood to flow to the heart while reducing its workload. 

Global Name

• Generic name:  Isosorbide mononitrate
• Brand names: Imdur, Monoket, and ISMO

Usage

What is Elantan used for? 

Elantan is prescribed to: 

• Prevent angina attacks. 

• Manage chronic heart failure alongside other medications. 

How do you use Elantan? 

Availability: 

Elantan is available in tablet and extended-release capsule forms. 

Dosage information: 

• Adults: The typical starting dose is 20 mg twice daily or 30-60 mg once daily for the extended-release form. 

• Children: Not recommended for use in children. 

• Elderlies: May require a lower dose due to a higher sensitivity to the effects of nitrates. 

Are the following suitable to take the drug: Children, adults, elderlies? 

• Children: Not suitable. 

• Adults: Suitable. 

• Elderlies: Suitable, with potential dose adjustments. 

Is there anyone who can’t take Elantan? 

• Children: Not recommended. 

• Adults: Individuals with severe anemia, hypotension, or those who have recently had a heart attack should not use Elantan. 

• Elderlies: Suitable, but dose adjustments may be necessary. 

• Pregnancy: Should be used only if clearly needed and under a doctor's supervision. 

• Lactation: Not recommended as it is unknown if it passes into breast milk. 

Allergies: Those allergic to isosorbide mononitrate or other nitrates should avoid Elantan. 

Warnings and precautions: Elantan should not be used in conjunction with erectile dysfunction medications like sildenafil, tadalafil, or vardenafil, as this can lead to severe hypotension. It should be taken on an empty stomach. 

Interactions and contraindications of the drug: 
Elantan should not be used with medications for erectile dysfunction or riociguat, as these can cause severe low blood pressure. It is contraindicated in patients with hypertrophic cardiomyopathy and severe hypotension. 

Side Effects

Users may experience flushing, headaches, dizziness, or lightheadedness as common side effects. Severe reactions include fainting, severe hypotension, and increased angina symptoms. 

Pharmacist Tips

• Storage information: Store at room temperature, away from direct light and moisture. 

• Handling instructions: Do not crush or chew the extended-release capsules; swallow them whole to ensure proper medication release. 

Availability

Where is Elantan available in Hong Kong?

 Elantan is a prescription medication that can be prescribed by healthcare providers.

FAQs

How should I take Elantan to avoid tolerance?  

It's best to have a drug-free period of 12-14 hours each day to prevent tolerance. Typically, this is achieved by taking the medication in the morning and skipping the evening dose.  

Can Elantan be used during a sudden angina attack?  

No, Elantan is not intended for relief of acute angina attacks. It is used for prevention. Use fast-acting nitroglycerin for acute attacks. 

What should I do if I miss a dose? 

Take it as soon as you remember, but skip it if it's almost time for your next dose. Do not double the dose. 

Can I drink alcohol while taking Elantan? 

Alcohol may worsen certain side effects of Elantan, such as dizziness and lightheadedness. It's best to limit or avoid alcoholic beverages.