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Actifed Syrup

Actifed Syrup is used primarily to treat symptoms associated with the common cold, allergies, and hay fever.

Last Modified: 08 May 2024

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What is Actifed Syrup? 

Actifed Syrup is a combination medication that contains two primary ingredients: triprolidine hydrochloride, an antihistamine that helps reduce allergy symptoms, and pseudoephedrine hydrochloride, a decongestant that relieves nasal congestion. This syrup is typically a clear, red liquid with a sweet taste, designed for oral use. 

The structure of Actifed Syrup is a carefully balanced liquid solution, ensuring that each dose delivers a consistent amount of the active ingredients. It is produced through pharmaceutical compounding, which combines the active compounds with syrupy bases and flavoring agents to make it palatable. 

Global Name

Generic name: Triprolidine and Pseudoephedrine Combination Syrup
Brand name: Actifed Cold & Allergy, Actifed Plus, and several others depending on the region and manufacturer. 


What is Actifed Syrup used for? 

Actifed Syrup is used primarily to treat symptoms associated with the common cold, allergies, and hay fever. These symptoms include: 

  • Sneezing 
  • Runny or stuffy nose 
  • Itchy, watery eyes 
  • Sinus congestion and pressure 

How do you use Actifed Syrup? 

Availability: Actifed Syrup is available as an oral liquid syrup. 

Dosage information: 

  • Children 6-12 years: 1 teaspoonful (5 ml) every 4-6 hours, not to exceed 6 teaspoonfuls in 24 hours. 
  • Adults and children over 12 years: 2 teaspoonfuls (10 ml) every 4-6 hours, not to exceed 12 teaspoonfuls in 24 hours. 


  • Children: Suitable for children over 6 years with reduced dosage. 
  • Adults: Suitable with standard dosage. 
  • Elderlies: Suitable with caution due to possible increased sensitivity to side effects. 

Who can’t take Actifed Syrup? 

  • Children under 6 years 
  • Adults with severe hypertension or coronary artery disease 
  • Elderlies with sensitivity to sympathomimetics 
  • Pregnancy: Consult with a doctor before use 
  • Lactation: Not recommended without medical advice 

Allergies: Avoid if allergic to any of the syrup’s components. 

  • Warnings and precautions: This medication should be taken with food to reduce gastrointestinal discomfort. Caution for patients with glaucoma, heart disease, thyroid disorders and prostate enlargement. Please seek medical advice before use. 

Interactions and contraindications: 

  • Do not use with MAO inhibitors or within 14 days of stopping them. 
  • Caution when used with other central nervous system depressants and alcoholic beverages. 

Side Effects

Common side effects include drowsiness, dizziness, headache, flushing or dry mouth. Contact a doctor if severe side effects occur. 

Pharmacist Tips

  • Storage information: Store at room temperature, away from light and moisture. 
  • Handling instructions: Use the measuring device that comes with the product for accuracy. 


Where is Actifed Syrup available in Hong Kong?

Actifed Syrup is an over-the-counter (OTC) medication that can be sold without a prescription. It is found in all chain drug stores, including Mannings and Watsons.


Is Actifed Syrup for purchase over-the-counter?

Yes, Actifed Syrup is available over-the-counter in many countries, but it is always best to consult with a healthcare provider before use.

Can Actifed Syrup be used for a cough?

Actifed Syrup is not primarily used for cough relief unless the cough is due to throat irritation from blocked nasal drainage or allergies.

How quickly does Actifed Syrup work?

Actifed Syrup generally starts to work within 30 minutes of ingestion, with peak effects occurring within 1 to 2 hours. 

This website provides content related to drug use and medicine for informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Do not use the information on this website to diagnose or treat a health problem or disease without consulting a qualified healthcare provider. The website's owners and contributors are not liable for any repercussions, adverse effects, or consequences resulting from the use of any medication or information provided herein.

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