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Is PrEP Safer Than Condoms? Understanding HIV Prevention in Hong Kong

Reviewed by Dr. Winston Goh

In the ongoing fight against HIV, prevention remains a critical aspect of maintaining public health. PrEP (pre-exposure prophylaxis) and condoms are two popular methods for reducing the risk of HIV transmission. In this blog post, we will discuss these methods, their safety, effectiveness and how to access PrEP in Hong Kong to ensure you make informed decisions about your sexual health.

What is PrEP (Pre-Exposure Prophylaxis)?

Pre-exposure prophylaxis, or PrEP, is a HIV prevention drug that involves taking a daily medication to reduce the risk of contracting HIV. The medication works by blocking the virus's ability to establish an infection in the body. When taken consistently and as prescribed, PrEP is highly effective at preventing HIV transmission, reducing the risk by up to 99%1.

There are currently two approved PrEP medications in Hong Kong: Truvada and Descovy. Both medications have demonstrated high levels of effectiveness in clinical trials, although Descovy is not recommended for individuals at risk of HIV through receptive vaginal sex2.

The Role of Condoms in HIV Prevention

Condoms are widely used as a physical barrier to prevent the transmission of HIV and other sexually transmitted infections (STIs). When used correctly and consistently, condoms can be up to 99.5% effective in preventing HIV transmission3. Condoms also provide protection against other STIs such as chlamydia, gonorrhoea, and syphilis in addition to HIV.

While condoms are an essential tool in HIV prevention, they are not without limitations. Condoms may occasionally break or slip off during sexual activity, reducing their effectiveness. Furthermore, they rely on consistent and correct use to provide optimal protection.

Comparing PrEP and Condoms: Safety and Effectiveness

PrEP and condoms both play significant roles in HIV prevention, but their safety and effectiveness vary depending on individual circumstances.


  • Highly effective when taken consistently and as prescribed (up to 99% reduction in HIV risk1)
  • Provides continuous protection, regardless of when sexual activity occurs
  • Requires regular monitoring and prescription by a healthcare professional
  • Does not protect against other STIs


  • Effective when used correctly and consistently (up to 98% reduction in HIV risk3)
  • Provides protection against HIV and other STIs
  • Requires correct use during each sexual encounter
  • May break or slip off, reducing effectiveness

In certain situations, PrEP may be more suitable than condoms, particularly for individuals at a higher risk of HIV exposure. For instance, those with an HIV-positive partner, a history of inconsistent condom use, or engaging in sex work may benefit from PrEP's continuous protection.

However, it is essential to remember that condoms are still necessary for preventing other STIs and for comprehensive protection, a combination of PrEP and condoms is recommended.

HIV Risk Reduction: Integrating PrEP and Condoms

A comprehensive approach to HIV prevention should include both PrEP and condoms. By using PrEP consistently and correctly, individuals can significantly reduce their risk of HIV transmission. Additionally, using condoms during sexual encounters helps protect against other STIs and further minimises the risk of HIV.

Other safer sex practices to consider include regular testing for HIV and other STIs, open communication with partners about sexual health, and reducing the number of sexual partners.

Accessing PrEP in Hong Kong 

PrEP is available in Hong Kong through private healthcare providers. To access PrEP, you will need a prescription from a qualified healthcare professional. This process typically involves an initial consultation, HIV testing, and kidney function tests to ensure PrEP is safe and appropriate for you.

Once prescribed, you will need to have regular follow-up appointments for HIV testing, STI screening, and monitoring of kidney function.


Adequate sex education knowledge and understanding the differences between PrEP and condoms, as well as their respective roles in HIV prevention, is crucial for making informed decisions about your sexual health. While PrEP offers significant protection against HIV, it is essential to continue using condoms for comprehensive protection against other STIs.

To determine the best approach for your individual needs, consult with a healthcare professional. They can provide guidance on PrEP, condoms, and other strategies for maintaining optimal sexual health.


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(1) US CDC. Effectiveness of Prevention Strategies to Reduce the Risk of Acquiring or Transmitting HIV. Retrieved May 17, 2023, from

(2) FDA. FDA approves second drug to prevent HIV infection as part of ongoing efforts to end the HIV epidemic. Retrieved May 17, 2023, from

(3) Aidsmap. Condoms. Retrieved May 17, 2023, from

Topics: Women's Health, LGBTQ+, Men's Health, Sexual Health

Dr Winston Goh

Dr Winston Goh

Family Medicine, General Practice