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Ezetrol, known generically as ezetimibe, is a medication used to treat high cholesterol.

Last Modified: 03 May 2024

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What is Ezetrol? 

Ezetrol, known generically as ezetimibe, is a medication used to treat high cholesterol. It works by inhibition of a small intestinal brush border transporter effectively reducing the amount of cholesterol absorbed by your body from the intestines. Ezetrol does not belong to the “statin” class of lipid-lowering medications which work on a different pathway. 

Ezetimibe, the active ingredient in Ezetrol, is a synthetic compound. It is structurally different from other classes of lipid-lowering compounds. The medication is formulated as a tablet, which is taken orally. 

Global Name

Generic name: Ezetimibe
Brand names:  Zetia, Ezetrol


What is Ezetrol used for? 

Ezetrol is used to lower levels of total cholesterol, LDL (bad cholesterol), and other fatty substances in the blood. It is often prescribed to treat the following conditions: 

  • Hypercholesterolemia (high cholesterol) 
  • Homozygous Familial Hypercholesterolemia (a genetic condition that results in high cholesterol levels) 
  • Sitosterolemia (a rare inherited condition that results in high cholesterol levels) 

How do you use Ezetrol? 


Ezetrol is available in tablet form. 

Dosage information:

  • The typical dose for adults and children 10 years of age and older is 10 mg once daily. 
  • Dosage does not typically vary by age. 


  • Children: Safe for children 10 years and older. 
  • Adults: Suitable for adults. 
  • Elderlies: Suitable for elderly patients. 

Is there anyone who can’t take Ezetrol? 

  • Children: Not recommended for children under 10 years. 
  • Adults: Most adults can take Ezetrol, but it should be used with caution in patients with liver problems. 
  • Elderlies: No dose adjustment is necessary for the elderly. 
  • Pregnancy: Should be used during pregnancy only if clearly needed. Alternative medication is advised as first choice instead like bile acid sequestrants. 
  • Lactation: It is not known if Ezetrol is excreted in breast milk; consult a healthcare provider before use. Alternative medication is advised to be utilized instead and avoid Ezetrol until further conclusive studies have established safety. 
  • Allergies: Individuals who are hypersensitive to ezetimibe or any component of the formulation should not take Ezetrol.

Warnings and Precautions:

Patients with liver problems should use Ezetrol with caution. It is important to have regular cholesterol level checks to monitor the drug's effectiveness. 

Drug Interactions: 

Ezetrol may interact with certain medications such as fibrates and bile acid sequestrants. It is also contraindicated in patients who have active liver disease. 


Side Effects

Some reported side effects include upper respiratory tract infections, diarrhea, joint pain, and fatigue. 

Pharmacist Tips

Storage information:

  • Store at room temperature away from moisture and heat. 

Handling instructions:

  • Handle the tablets with clean, dry hands and only remove them from the blister pack when ready to take. 


Where is Ezetrol available in Hong Kong?

Ezetrol is a prescription medication that can be prescribed by healthcare providers. 



How does Ezetrol work to lower cholesterol?

Ezetrol works by blocking the absorption of cholesterol from the small intestine, leading to a reduction in blood cholesterol levels.

Can Ezetrol be taken with statins?

Yes, Ezetrol is often prescribed alongside statins to enhance cholesterol-lowering effects.

How quickly can I expect results after starting Ezetrol? 

Cholesterol levels typically begin to lower within 2 weeks, with significant results seen within 4 to 6 weeks.

What dietary changes should I consider while taking Ezetrol?

For best results, it's recommended to follow a cholesterol-lowering, low saturated fat diet alongside your Ezetrol medication. Consult a healthcare provider for dietary advice. 

This website provides content related to drug use and medicine for informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Do not use the information on this website to diagnose or treat a health problem or disease without consulting a qualified healthcare provider. The website's owners and contributors are not liable for any repercussions, adverse effects, or consequences resulting from the use of any medication or information provided herein.

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