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Buscopan, also known as hyoscine butylbromide, is an antispasmodic medication made from the purified extract of the plant Duboisia.

Last Modified: 22 May 2024

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What is Buscopan? 

Buscopan, also known as hyoscine butylbromide and scopolamine butylbromide, is an antispasmodic medication made from the purified extract of the plant Duboisia. It primarily contains the chemical N-butylscopolammonium bromide as its active ingredient. 

N-butylscopolammonium bromide (Hyoscine/scopolamine butylbromide), the active compound in Buscopan, is a quaternary ammonium compound derivative of scopolamine. It is synthesized in a multi-step chemical process that results in a water-soluble form that's less likely to cross the blood-brain barrier, minimizing central nervous system side effects. 

Global Name

Generic Names: 

The generic name for Buscopan is Hyoscine Butylbromide or Scopolamine butylbromide.


Global Brands:  

  • Buscopan is one of the brand names used in United Kingdom, Canada, Australia, Germany, Brazil, Philippines and Egypt.  
  • Scopolamine Butylbromide is one of the brand names used in India and South Africa.
*Note: In the United States, Buscopan currently has no FDA approval for human use. 



What is Buscopan used for?

Buscopan alleviates cramps and spasms of the stomach, intestines, and bladder. It is commonly used to treat conditions like irritable bowel syndrome (IBS), menstrual cramps, and other similar gastrointestinal or genitourinary issues. 

How Do You Use Buscopan? 


Buscopan is available in tablet form, injectable solution, and suppositories. 

  • Dosage information: 
  • Adults: Typically, 10 mg tablets taken three to five times a day. 
  • Children: Dosage varies depending on age and weight; consult a pediatrician. 


Are the following suitable to take the drug: Children, adults, elderlies? 

  • Children: With a doctor's recommendation. 
  • Adults: Yes. 
  • Elderlies: Yes, but with caution due to potential sensitivity to anticholinergic effects. 


Is there anyone who can’t take Buscopan? 

  • Children: Not recommended for young children without medical advice. 
  • Adults: Adults with certain medical conditions such as myasthenia gravis, glaucoma, prostate enlargement, megacolon and gastrointestinal obstruction need to avoid it. 
  • Elderlies: May be used, but with increased caution. 
  • Pregnancy and Lactation: Not recommended unless clearly necessary and prescribed by a doctor. 


Any allergies people might have that aren’t suitable to take the drug? 

Individuals allergic to hyoscine (scopolamine) butylbromide and/or excipients of the formed drug or other belladonna alkaloids should not take Buscopan. 


Any warnings and precautions? 

Take Buscopan after meals if gastrointestinal irritation occurs. 


Drug Interactions

Buscopan can interact with other anticholinergic drugs and may enhance the effects of certain medications like antihistamines, antidepressants, or antipsychotics. 

Side Effects

Common side effects include flushed skin, dry mouth, blurred vision, and constipation. Severe side effects are rare but can include hallucinations, urinary retention and heart palpitations. 


Pharmacist Tips

  • Starting Buscopan: Begin with the lowest dose and do not exceed the prescribed amount without consulting a doctor. 
  • Missed Dose: Take it as soon as you remember, unless it's nearly time for the next dose. Avoid doubling up. 
  • Alcohol and Drowsiness: Steer clear of alcohol and be cautious when performing tasks requiring alertness. 
  • Storage Information: Keep at room temperature in a dry place, away from direct sunlight. 
  • Traveling with Medication: Carry in its original labeled container with your prescription. 
  • Disposal of Unused Medication: Dispose of Buscopan responsibly; consult your pharmacist for proper disposal methods. 
  • Handling Instructions: Handle tablets with dry hands and directly consume after removing from the package. 
  • Regular Checkups: Schedule periodic appointments to monitor Buscopan's effectiveness. 
  • Adherence to Therapy: Continue to take Buscopan as directed, even if symptoms improve. 
  • Diet and Hydration: Maintain a good diet and hydration to counteract potential dry mouth or constipation. 


Where is Buscopan available in Hong Kong?

Buscopan is an over-the-counter (OTC) medication that can be sold without a prescription. It is found in all chain drug stores, including Mannings and Watsons. 


Is Buscopan for purchase over the counter?  

In some countries, Buscopan is available over the counter, while in others, it may require a prescription. 

How quickly does Buscopan work? 

Buscopan typically starts to relieve symptoms within 15 minutes of oral administration. 

Can Buscopan be taken long-term? 

It is usually prescribed for short-term relief. Long-term use should be under medical supervision. 

What does Buscopan do?  

Buscopan (Hyoscine (scopolamine) Butylbromide) is an antispasmodic medication that relieves muscle cramps in the digestive and genito-urinary tracts by blocking the action of acetylcholine, a neurotransmitter that causes muscle contractions. 

Always consult a healthcare professional for personal medical advice and read the product information leaflet before use. 

This website provides content related to drug use and medicine for informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Do not use the information on this website to diagnose or treat a health problem or disease without consulting a qualified healthcare provider. The website's owners and contributors are not liable for any repercussions, adverse effects, or consequences resulting from the use of any medication or information provided herein.

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